Big Pharma had a plan.
It designed a trial for a COX-2 drug and it ran.
Yet it wasn’t enough to get pain low.
We’re still here in the land of no?
Fiddle with the randomizing, a doctor said.
The drug’s not to blame.
All clinical trials simply are not the same.
When comparing just the right subjects in a test,
you’ll clearly get an effect that’s the best.
Would you like to try it?
Why, yes. Yes, we would.
Big Pharma took the bait. Since Big Pharma re-powered the trial,
Its COX-2 CV effects were much less.
With deception and guile,
It’s the land of success.
Reset your trial parameters and you just might declare,
I’m a blockbuster success.
Now you’re getting somewhere.